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Die Bildung und Aggregation des Amyloid-beta-Proteins ist ein komplexer Prozess.
Alzheimer therapy from Jülich passes another important test
Jülich/Vienna, 10 May 2019 – The Alzheimer drug candidate PRI-002 developed at Forschungszentrum Jülich has successfully completed Phase I of clinical research involving healthy volunteers. When administered daily over a period of four weeks, the active substance proved to be safe for use in humans. The next milestone will be the proof of efficacy in patients in clinical Phase II.
More: Alzheimer therapy from Jülich passes another important test …

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Autophagie (Platzhalter)

Autophagy

Autophagy is a highly conserved mechanism in eukaryotes to degrade cellular components. Autophagy plays an important role both in the baseline turnover of intracellular proteins and organelles, as well as in the production of amino acids under starvation conditions. We investigate proteins that are involved in this process. More: Autophagy …

Alzheimer2

Alzheimer′ s Disease

Alzheimer´s disease is a progressive, neurodegenerative disorder and the most common type of dementia. Currently more than 24 million people are affected worldwide. Our research focusses on developing methods for pre-symptomatic diagnosis and new therapeutic approaches. More: Alzheimer′ s Disease …

NMR-Teaser

Biomolecular NMR Center

The Biomolecular NMR Center, which is jointly run by the Institute of Physical Biology at HHU Düsseldorf and the ICS-6, operates various high-field NMR machines and provides an excellent environment for liquid and solid state NMR spectroscopy for structural biology on biologically and medically relevant proteins. More: Biomolecular NMR Center …


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